Adenosine disodium triphosphate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

三磷酸腺苷 (ATP) 是一种三磷酸核苷，在细胞中用作辅酶，通常被称为细胞内能量转移的“货币分子单位”。

Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.

ATP disodium salt hydrate (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.ATP disodium salt hydrate (2 mM; 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.?ATP disodium salt hydrate stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis.

ATP disodium salt hydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.ATP disodium salt hydrate induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo. Animal Model:Four-week-old Kunming mice (18-22 g)Dosage:50 mg/kg Administration:Intraperitoneal injection, before bacterial (E. coli) challengeResult:Protected mice from bacterial infection.

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Others

Other Targets

Others

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34369-07-8

551.15

C10H14N5Na2O13P3

>98% (HPLC)

In Vitro:?H2O : 100 mg/mL

c1nc2c(c(n1)N)ncn2C1[C@@H]([C@@H]([C@H](O1)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O.O.[Na+].[Na+]

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(-20℃)

With Ice Pack

≥ 2 years